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Chemotherapy for People with Gynanecological Cancer




  • Outlines the main objectives of chemotherapy
  • Informs about the administration of chemotherapy treatments
  • Includes a tabulated summary of commonly used chemotherapy drugs and their side-effects
  • Summarises the side-effects associated with chemotherapy treatments, how to assess them and how they can be managed

Chemotherapy plays an important role in the cure and palliation of women with gynaecological cancers, but it is associated with significant physical and psychological distress. The provision of information before commencing treatment can greatly assist in helping women to address their concerns and cope with the experience. In this chapter learn more about chemotherapy; its purposes, administration and side-effects. Also, understand more about new target therapies.


Contents include

  • Mode of action
  • Administration
    • Treatment cycles
    • Dose intensity
    • Routes of administration
  • Side-effects
    • General
    • Effects on bone marrow
    • Nausea and vomiting
    • Constipation
    • Diarrhoea
    • Oral mucositis
    • Alopecia
    • Peripheral neuropathy
    • Fatigue
    • Effects on reproductive organs
    • Palmar plantar erythrodysesthesia
    • Infusion reactions
    • Secondary malignancy
  • Targeted therapies
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Author / Editor Biographies

Sheila MacBride is a registered nurse with a bachelor's degree in nursing, a master's degree in cancer nursing, and a postgraduate certificate in teaching and learning in higher education. Her master's thesis focused on survivorship and follow-up issues in young men who received chemotherapy for testicular cancer. Sheila has worked as a cancer nurse in Scotland for twenty years, holding posts as charge nurse, Clinical Nurse Specialist, and Clinical Nursing (education) Facilitator. She developed a nurse led chemotherapy service in South-East Scotland. For the past two years she has been a lectu...
Ellen Toms is a registered nurse who holds a diploma in professional studies (nursing), a bachelor's degree in cancer nursing (with honours), and a master's degree in advanced clinical practice cancer nursing. Her formative nursing years were spent in general gynaecology while completing her diploma in professional studies. She then moved to the gynaecological oncology ward at the Royal Marsden Hospital (London, UK), followed by a ward manager's position in a 50 bed gynaecology unit. Ellen then helped to set up the gynaecological oncology ward and service at Portsmouth Hospital (UK), before mo...

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